Intestinal Immunity and Gut Microbiota in Atherogenesis

Intestinal Immunity and Gut Microbiota in Atherogenesis

Atherosclerosis is a chronic inflammatory disease. Interventions targeting the inflammatory process could provide new strategies for preventing atherosclerotic cardiovascular diseases (CVD). Previously, we have reported that oral administration of anti-CD3 antibodies, or active vitamin D3, reduced atherosclerosis in mice via recruiting regulatory T cells and tolerogenic dendritic cells to the g...

Immunity, gut microbiota and infection

Recurrent infections are very common in children and a major challenge for pediatricians. They affect the children’s quality of life, cause absences from school and lost parental working days, and repeated medical examinations, hospital admissions as well as antibiotic therapies lead to high costs for society. Given their prevalence and clinical importance, various prevention strategies have be...

Gut Microbiota and Neuropsychiatric Disorders

Perinatal programming of gut microbiota and immunity.

High frequencies of antibiotic resistance genes in infants’ meconium and early fecal samples M. J. Gosalbes and Y. Vallès and N. Jiménez-Hernández and C. Balle and P. Riva and S. Miravet-Verde and L. E. de Vries and S. Llop and Y. Agersø and S. J. Sørensen and F. Ballester and M. P. Francino Journal of Developmental Origins of Health and Disease, Volume 7, Issue 01, February 2016, pp 35-44 doi:...

Gut barrier structure, mucosal immunity and intestinal microbiota in the pathogenesis and treatment of HIV infection

Over the past 10 years, extensive work has been carried out in the field of microbial translocation in HIV infection, ranging from studies on its clinical significance to investigations on its pathogenic features. In the present work, we review the most recent findings on this phenomenon, focusing on the predictive role of microbial translocation in HIV-related morbidity and mortality, the mech...